Clinical and ultrastructural studies in duodenal pseudomelanosis.

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Clinical and ultrastructural studies in duodenal pseudomelanosis.

Nine patients with duodenal pseudomelanosis are described: seven had endstage renal failure while one other patient had undergone renal transplantation. Eight of the nine had been on oral iron supplements. The pigment stained positively with Perls' stain for iron in five patients, positively with the Masson-Fontana method normally used to identify melanin in one, and positively with both method...

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Peppered and rare – Gastric and Duodenal Pseudomelanosis: A case series

Upper Gastrointestinal (GI) pseudomelanosis is an uncommon entity characterized by endoscopic visualization of speckled dark mucosal pigmentation. While described in the rectum and colon, 'melanosis' or more aptly 'pseudomelanosis' is rare in the duodenum and exceedingly rare in the stomach. Five cases of pseudomelanosis were encountered at our department. Four females and one male were diagnos...

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Gastrointestinal pseudomelanosis

An 81-year-old Caucasian woman with a history of hypertension, stage IV chronic kidney disease and iron defi ciency anemia was evaluated for a 3-month history of common bile duct dilation (16 mm). Physical exam was unremarkable with stable vital signs. Laboratory tests were signifi cant for a hemoglobin ranging from 8.4-10.0 g/dL (reference range: 12.0-15.0 g/dL) and creatinine ranging from 2.4...

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Gastric and Duodenal Pseudomelanosis: An Extended Unusual Finding in a Patient with End Stage Kidney Disease

Gastric and duodenal pseudomelanosis is a rare endoscopic mucosal finding, characterized by the accumulation of iron in macrophages of the lamina propria of the stomach and duodenum. The clinical significance and long term sequelae have not been clarified yet. However, this benign condition is associated with a variety of clinical conditions, such as essential hypertension, chronic renal failur...

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Pseudomelanosis Duodeni

A 55-year-old male with history of coronary artery disease, chronic kidney disease stage 4, diabetes mellitus, uncontrolled hypertension (on multiple antihypertensive medications), and iron deficiency anemia was referred for esophagogastroduodenoscopy (EGD) for evaluation of intractable nausea and vomiting. EGD showed black speckled pigmentation of the duodenal mucosa (Figure 1). Duodenal biops...

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ژورنال

عنوان ژورنال: Gut

سال: 1987

ISSN: 0017-5749

DOI: 10.1136/gut.28.12.1673